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MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation.
Baluapuri A, Hofstetter J, Dudvarski Stankovic N, Endres T, Bhandare P, Vos SM, Adhikari B, Schwarz JD, Narain A, Vogt M, Wang SY, Düster R, Jung LA, Vanselow JT, Wiegering A, Geyer M, Maric HM, Gallant P, Walz S, Schlosser A, Cramer P, Eilers M, Wolf E. Baluapuri A, et al. Among authors: hofstetter j. Mol Cell. 2019 May 16;74(4):674-687.e11. doi: 10.1016/j.molcel.2019.02.031. Epub 2019 Mar 27. Mol Cell. 2019. PMID: 30928206 Free PMC article.
Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle.
Büchel G, Carstensen A, Mak KY, Roeschert I, Leen E, Sumara O, Hofstetter J, Herold S, Kalb J, Baluapuri A, Poon E, Kwok C, Chesler L, Maric HM, Rickman DS, Wolf E, Bayliss R, Walz S, Eilers M. Büchel G, et al. Among authors: hofstetter j. Cell Rep. 2017 Dec 19;21(12):3483-3497. doi: 10.1016/j.celrep.2017.11.090. Cell Rep. 2017. PMID: 29262328 Free PMC article.
PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.
Adhikari B, Bozilovic J, Diebold M, Schwarz JD, Hofstetter J, Schröder M, Wanior M, Narain A, Vogt M, Dudvarski Stankovic N, Baluapuri A, Schönemann L, Eing L, Bhandare P, Kuster B, Schlosser A, Heinzlmeir S, Sotriffer C, Knapp S, Wolf E. Adhikari B, et al. Among authors: hofstetter j. Nat Chem Biol. 2020 Nov;16(11):1179-1188. doi: 10.1038/s41589-020-00652-y. Epub 2020 Sep 28. Nat Chem Biol. 2020. PMID: 32989298 Free PMC article.
Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma.
Schick M, Zhang L, Maurer S, Maurer HC, Isaakaidis K, Schneider L, Patra U, Schunck K, Rohleder E, Hofstetter J, Baluapuri A, Scherger AK, Slotta-Huspenina J, Hettler F, Weber J, Engleitner T, Maresch R, Slawska J, Lewis R, Istvanffy R, Habringer S, Steiger K, Baiker A, Oostendorp RAJ, Miething C, Lenhof HP, Bassermann F, Chapuy B, Wirth M, Wolf E, Rad R, Müller S, Keller U. Schick M, et al. Among authors: hofstetter j. Nat Commun. 2022 Jan 12;13(1):281. doi: 10.1038/s41467-021-27704-8. Nat Commun. 2022. PMID: 35022408 Free PMC article.
Nucleolar detention of NONO shields DNA double-strand breaks from aberrant transcripts.
Trifault B, Mamontova V, Cossa G, Ganskih S, Wei Y, Hofstetter J, Bhandare P, Baluapuri A, Nieto B, Solvie D, Ade CP, Gallant P, Wolf E, Larsen DH, Munschauer M, Burger K. Trifault B, et al. Among authors: hofstetter j. Nucleic Acids Res. 2024 Apr 12;52(6):3050-3068. doi: 10.1093/nar/gkae022. Nucleic Acids Res. 2024. PMID: 38224452 Free PMC article.
MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress.
Sipol A, Hameister E, Xue B, Hofstetter J, Barenboim M, Öllinger R, Jain G, Prexler C, Rubio RA, Baldauf MC, Franchina DG, Petry A, Schmäh J, Thiel U, Görlach A, Cario G, Brenner D, Richter GHS, Grünewald TGP, Rad R, Wolf E, Ruland J, Sorensen PH, Burdach SEG. Sipol A, et al. Among authors: hofstetter j. Blood. 2022 Feb 24;139(8):1184-1197. doi: 10.1182/blood.2020007932. Blood. 2022. PMID: 33908607 Free PMC article.
Correlates of Risk for Disinhibited Behaviors in the Million Veteran Program Cohort.
Barr PB, Bigdeli TB, Meyers JL, Peterson RE, Sanchez-Roige S, Mallard TT, Dick DM, Harden KP, Wilkinson A, Graham DP, Nielsen DA, Swann AC, Lipsky RK, Kosten TR, Aslan M, Harvey PD, Kimbrel NA, Beckham JC; Million Veteran Program (MVP)Cooperative Studies Program (CSP) #572. Barr PB, et al. JAMA Psychiatry. 2024 Feb 1;81(2):188-197. doi: 10.1001/jamapsychiatry.2023.4141. JAMA Psychiatry. 2024. PMID: 37938835
Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia, Bipolar Disorder, and Depression Among Adults in the US Veterans Affairs Health Care System.
Bigdeli TB, Voloudakis G, Barr PB, Gorman BR, Genovese G, Peterson RE, Burstein DE, Velicu VI, Li Y, Gupta R, Mattheisen M, Tomasi S, Rajeevan N, Sayward F, Radhakrishnan K, Natarajan S, Malhotra AK, Shi Y, Zhao H, Kosten TR, Concato J, O'Leary TJ, Przygodzki R, Gleason T, Pyarajan S, Brophy M, Huang GD, Muralidhar S, Gaziano JM, Aslan M, Fanous AH, Harvey PD, Roussos P; Cooperative Studies Program (CSP) #572 and Million Veteran Program (MVP). Bigdeli TB, et al. JAMA Psychiatry. 2022 Sep 14;79(11):1092-101. doi: 10.1001/jamapsychiatry.2022.2742. Online ahead of print. JAMA Psychiatry. 2022. PMID: 36103194 Free PMC article.
203 results