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A spike in inflammation.
Johnson BM, Junkins RD, Ting JP. Johnson BM, et al. Nat Nanotechnol. 2018 Nov;13(11):980-981. doi: 10.1038/s41565-018-0292-y. Nat Nanotechnol. 2018. PMID: 30374158 No abstract available.
STING Agonist Mitigates Experimental Autoimmune Encephalomyelitis by Stimulating Type I IFN-Dependent and -Independent Immune-Regulatory Pathways.
Johnson BM, Uchimura T, Gallovic MD, Thamilarasan M, Chou WC, Gibson SA, Deng M, Tam JW, Batty CJ, Williams J, Matsushima GK, Bachelder EM, Ainslie KM, Markovic-Plese S, Ting JP. Johnson BM, et al. J Immunol. 2021 May 1;206(9):2015-2028. doi: 10.4049/jimmunol.2001317. Epub 2021 Apr 5. J Immunol. 2021. PMID: 33820855 Free PMC article.
STING-induced regulatory B cells compromise NK function in cancer immunity.
Li S, Mirlekar B, Johnson BM, Brickey WJ, Wrobel JA, Yang N, Song D, Entwistle S, Tan X, Deng M, Cui Y, Li W, Vincent BG, Gale M Jr, Pylayeva-Gupta Y, Ting JP. Li S, et al. Among authors: johnson bm. Nature. 2022 Oct;610(7931):373-380. doi: 10.1038/s41586-022-05254-3. Epub 2022 Oct 5. Nature. 2022. PMID: 36198789 Free PMC article.
A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1-insensitive models of triple-negative breast cancer.
Cheng N, Watkins-Schulz R, Junkins RD, David CN, Johnson BM, Montgomery SA, Peine KJ, Darr DB, Yuan H, McKinnon KP, Liu Q, Miao L, Huang L, Bachelder EM, Ainslie KM, Ting JP. Cheng N, et al. Among authors: johnson bm. JCI Insight. 2018 Nov 15;3(22):e120638. doi: 10.1172/jci.insight.120638. JCI Insight. 2018. PMID: 30429378 Free PMC article.
A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination.
Junkins RD, Gallovic MD, Johnson BM, Collier MA, Watkins-Schulz R, Cheng N, David CN, McGee CE, Sempowski GD, Shterev I, McKinnon K, Bachelder EM, Ainslie KM, Ting JP. Junkins RD, et al. J Control Release. 2018 Jan 28;270:1-13. doi: 10.1016/j.jconrel.2017.11.030. Epub 2017 Nov 21. J Control Release. 2018. PMID: 29170142 Free PMC article.
Acetalated Dextran Microparticles for Codelivery of STING and TLR7/8 Agonists.
Collier MA, Junkins RD, Gallovic MD, Johnson BM, Johnson MM, Macintyre AN, Sempowski GD, Bachelder EM, Ting JP, Ainslie KM. Collier MA, et al. Mol Pharm. 2018 Nov 5;15(11):4933-4946. doi: 10.1021/acs.molpharmaceut.8b00579. Epub 2018 Oct 15. Mol Pharm. 2018. PMID: 30281314 Free PMC article.
7,630 results