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PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.
Adhikari B, Bozilovic J, Diebold M, Schwarz JD, Hofstetter J, Schröder M, Wanior M, Narain A, Vogt M, Dudvarski Stankovic N, Baluapuri A, Schönemann L, Eing L, Bhandare P, Kuster B, Schlosser A, Heinzlmeir S, Sotriffer C, Knapp S, Wolf E. Adhikari B, et al. Among authors: schlosser a. Nat Chem Biol. 2020 Nov;16(11):1179-1188. doi: 10.1038/s41589-020-00652-y. Epub 2020 Sep 28. Nat Chem Biol. 2020. PMID: 32989298 Free PMC article.
MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation.
Baluapuri A, Hofstetter J, Dudvarski Stankovic N, Endres T, Bhandare P, Vos SM, Adhikari B, Schwarz JD, Narain A, Vogt M, Wang SY, Düster R, Jung LA, Vanselow JT, Wiegering A, Geyer M, Maric HM, Gallant P, Walz S, Schlosser A, Cramer P, Eilers M, Wolf E. Baluapuri A, et al. Among authors: schlosser a. Mol Cell. 2019 May 16;74(4):674-687.e11. doi: 10.1016/j.molcel.2019.02.031. Epub 2019 Mar 27. Mol Cell. 2019. PMID: 30928206 Free PMC article.
Ugi Reaction-Derived α-Acyl Aminocarboxamides Bind to Phosphatidylinositol 3-Kinase-Related Kinases, Inhibit HSF1-Dependent Heat Shock Response, and Induce Apoptosis in Multiple Myeloma Cells.
Bach M, Lehmann A, Brünnert D, Vanselow JT, Hartung A, Bargou RC, Holzgrabe U, Schlosser A, Chatterjee M. Bach M, et al. Among authors: schlosser a. J Med Chem. 2017 May 25;60(10):4147-4160. doi: 10.1021/acs.jmedchem.6b01613. Epub 2017 May 8. J Med Chem. 2017. PMID: 28453931
Architecture of the mycobacterial type VII secretion system.
Famelis N, Rivera-Calzada A, Degliesposti G, Wingender M, Mietrach N, Skehel JM, Fernandez-Leiro R, Böttcher B, Schlosser A, Llorca O, Geibel S. Famelis N, et al. Among authors: schlosser a. Nature. 2019 Dec;576(7786):321-325. doi: 10.1038/s41586-019-1633-1. Epub 2019 Oct 9. Nature. 2019. PMID: 31597161 Free PMC article.
289 results