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Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors.
J Med Chem. 2009 Sep 10;52(17):5271-94. doi: 10.1021/jm900552r.
J Med Chem. 2009.
PMID: 19601577
Review.
No abstract available.
Cellular iron depletion and the mechanisms involved in the iron-dependent regulation of the growth arrest and DNA damage family of genes.
Saletta F, Rahmanto YS, Siafakas AR, Richardson DR.
Saletta F, et al. Among authors: siafakas ar.
J Biol Chem. 2011 Oct 14;286(41):35396-35406. doi: 10.1074/jbc.M111.273060. Epub 2011 Aug 18.
J Biol Chem. 2011.
PMID: 21852233
Free PMC article.
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Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes.
Lane DJR, Bae DH, Siafakas AR, Suryo Rahmanto Y, Al-Akra L, Jansson PJ, Casero RA Jr, Richardson DR.
Lane DJR, et al. Among authors: siafakas ar.
Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt B):2793-2813. doi: 10.1016/j.bbadis.2018.05.007. Epub 2018 May 16.
Biochim Biophys Acta Mol Basis Dis. 2018.
PMID: 29777905
Free PMC article.
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Acireductone dioxygenase 1 (ADI1) is regulated by cellular iron by a mechanism involving the iron chaperone, PCBP1, with PCBP2 acting as a potential co-chaperone.
Bae DH, Lane DJR, Siafakas AR, Sutak R, Paluncic J, Huang MLH, Jansson PJ, Rahmanto YS, Richardson DR.
Bae DH, et al. Among authors: siafakas ar.
Biochim Biophys Acta Mol Basis Dis. 2020 Oct 1;1866(10):165844. doi: 10.1016/j.bbadis.2020.165844. Epub 2020 May 29.
Biochim Biophys Acta Mol Basis Dis. 2020.
PMID: 32480040
Free article.
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Cell wall-linked cryptococcal phospholipase B1 is a source of secreted enzyme and a determinant of cell wall integrity.
Siafakas AR, Sorrell TC, Wright LC, Wilson C, Larsen M, Boadle R, Williamson PR, Djordjevic JT.
Siafakas AR, et al.
J Biol Chem. 2007 Dec 28;282(52):37508-14. doi: 10.1074/jbc.M707913200. Epub 2007 Oct 18.
J Biol Chem. 2007.
PMID: 17947228
Free article.
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Lipid rafts in Cryptococcus neoformans concentrate the virulence determinants phospholipase B1 and Cu/Zn superoxide dismutase.
Siafakas AR, Wright LC, Sorrell TC, Djordjevic JT.
Siafakas AR, et al.
Eukaryot Cell. 2006 Mar;5(3):488-98. doi: 10.1128/EC.5.3.488-498.2006.
Eukaryot Cell. 2006.
PMID: 16524904
Free PMC article.
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Role and mechanism of phosphatidylinositol-specific phospholipase C in survival and virulence of Cryptococcus neoformans.
Chayakulkeeree M, Sorrell TC, Siafakas AR, Wilson CF, Pantarat N, Gerik KJ, Boadle R, Djordjevic JT.
Chayakulkeeree M, et al. Among authors: siafakas ar.
Mol Microbiol. 2008 Aug;69(4):809-26. doi: 10.1111/j.1365-2958.2008.06310.x. Epub 2008 Jun 4.
Mol Microbiol. 2008.
PMID: 18532984
Free article.
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