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The in vivo efficacy and side effect pharmacology of GS-5759, a novel bifunctional phosphodiesterase 4 inhibitor and long-acting β 2-adrenoceptor agonist in preclinical animal species.
Salmon M, Tannheimer SL, Gentzler TT, Cui ZH, Sorensen EA, Hartsough KC, Kim M, Purvis LJ, Barrett EG, McDonald JD, Rudolph K, Doyle-Eisele M, Kuehl PJ, Royer CM, Baker WR, Phillips GB, Wright CD. Salmon M, et al. Among authors: wright cd. Pharmacol Res Perspect. 2014 Aug;2(4):e00046. doi: 10.1002/prp2.46. Epub 2014 Jun 9. Pharmacol Res Perspect. 2014. PMID: 25505595 Free PMC article.
GS-5759, a Bifunctional β2-Adrenoceptor Agonist and Phosphodiesterase 4 Inhibitor for Chronic Obstructive Pulmonary Disease with a Unique Mode of Action: Effects on Gene Expression in Human Airway Epithelial Cells.
Joshi T, Yan D, Hamed O, Tannheimer SL, Phillips GB, Wright CD, Kim M, Salmon M, Newton R, Giembycz MA. Joshi T, et al. Among authors: wright cd. J Pharmacol Exp Ther. 2017 Feb;360(2):324-340. doi: 10.1124/jpet.116.237743. Epub 2016 Dec 7. J Pharmacol Exp Ther. 2017. PMID: 27927912
Microscopic Small Airway Abnormalities Identified in Early Idiopathic Pulmonary Fibrosis In Vivo Using Endobronchial Optical Coherence Tomography.
Berigei SR, Nandy S, Yamamoto S, Raphaely RA, DeCoursey A, Lee J, Sharma A, Auchincloss HG, Gaissert H, Lanuti M, Ott HC, Sachdeva UM, Wright CD, Zhao SH, Hallowell RW, Shea BS, Muniappan A, Keyes CM, Hariri LP. Berigei SR, et al. Among authors: wright cd. Am J Respir Crit Care Med. 2024 May 15. doi: 10.1164/rccm.202401-0249OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 38747674
A Pilot Study Using Machine Learning Algorithms and Wearable Technology for the Early Detection of Postoperative Complications After Cardiothoracic Surgery.
Beqari J, Powell J, Hurd J, Potter AL, McCarthy M, Srinivasan D, Wang D, Cranor J, Zhang L, Webster K, Kim J, Rosenstein A, Zheng Z, Lin TH, Li J, Fang Z, Zhang Y, Anderson A, Madsen J, Anderson J, Clark A, Yang ME, Nurko A, El-Jawahri AR, Sundt TM, Melnitchouk S, Jassar AS, D'Alessandro D, Panda N, Schumacher-Beal LY, Wright CD, Auchincloss HG, Sachdeva UM, Lanuti M, Colson YL, Langer N, Osho A, Yang CJ, Li X. Beqari J, et al. Among authors: wright cd. Ann Surg. 2024 Mar 14. doi: 10.1097/SLA.0000000000006263. Online ahead of print. Ann Surg. 2024. PMID: 38482684
383 results