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The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway.
Qyang Y, Martin-Puig S, Chiravuri M, Chen S, Xu H, Bu L, Jiang X, Lin L, Granger A, Moretti A, Caron L, Wu X, Clarke J, Taketo MM, Laugwitz KL, Moon RT, Gruber P, Evans SM, Ding S, Chien KR. Qyang Y, et al. Among authors: wu x. Cell Stem Cell. 2007 Aug 16;1(2):165-79. doi: 10.1016/j.stem.2007.05.018. Epub 2007 Jun 14. Cell Stem Cell. 2007. PMID: 18371348 Free article.
A small-molecule agonist of the Wnt signaling pathway.
Liu J, Wu X, Mitchell B, Kintner C, Ding S, Schultz PG. Liu J, et al. Among authors: wu x. Angew Chem Int Ed Engl. 2005 Mar 18;44(13):1987-90. doi: 10.1002/anie.200462552. Angew Chem Int Ed Engl. 2005. PMID: 15724259 No abstract available.
A small molecule primes embryonic stem cells for differentiation.
Zhu S, Wurdak H, Wang J, Lyssiotis CA, Peters EC, Cho CY, Wu X, Schultz PG. Zhu S, et al. Among authors: wu x. Cell Stem Cell. 2009 May 8;4(5):416-26. doi: 10.1016/j.stem.2009.04.001. Cell Stem Cell. 2009. PMID: 19427291 Free article.
Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma.
Chen EY, DeRan MT, Ignatius MS, Grandinetti KB, Clagg R, McCarthy KM, Lobbardi RM, Brockmann J, Keller C, Wu X, Langenau DM. Chen EY, et al. Among authors: wu x. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5349-54. doi: 10.1073/pnas.1317731111. Epub 2014 Mar 24. Proc Natl Acad Sci U S A. 2014. PMID: 24706870 Free PMC article.
Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription.
Li Q, Sun Y, Jarugumilli GK, Liu S, Dang K, Cotton JL, Xiol J, Chan PY, DeRan M, Ma L, Li R, Zhu LJ, Li JH, Leiter AB, Ip YT, Camargo FD, Luo X, Johnson RL, Wu X, Mao J. Li Q, et al. Among authors: wu x. Cell Stem Cell. 2020 May 7;26(5):675-692.e8. doi: 10.1016/j.stem.2020.03.002. Epub 2020 Apr 6. Cell Stem Cell. 2020. PMID: 32259481 Free PMC article.
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