Controlling exposure to laboratory animal allergens

ILAR J. 2001;42(1):17-36. doi: 10.1093/ilar.42.1.17.


Laboratory animal allergy (LAA) is a significant occupational disease that may affect up to one third of personnel exposed to laboratory animals. Research has characterized the relative risks of exposure, in terms of intensity, frequency, and duration, associated with given tasks and work areas in the animal facility. Studies have shown that reduced exposure to animal allergens can reduce the incidence of LAA and relieve symptoms among affected workers. A combination of measures to eliminate or control allergen exposure, including engineering and administrative controls and personal protective equipment, have been integral components of effective LAA management programs. The author provides a comprehensive review of exposure control options, considerations, and " best practices" relative to laboratory animal allergen in the context of traditional industrial hygiene methods.

Publication types

  • Review

MeSH terms

  • Air Pollutants, Occupational / adverse effects
  • Air Pollution, Indoor / adverse effects
  • Air Pollution, Indoor / prevention & control
  • Allergens / adverse effects
  • Allergens / immunology*
  • Allergens / urine
  • Animal Husbandry / instrumentation
  • Animal Husbandry / methods
  • Animal Technicians
  • Animals
  • Animals, Laboratory / immunology*
  • Environment, Controlled*
  • Humans
  • National Institute for Occupational Safety and Health, U.S.
  • Occupational Diseases / immunology
  • Occupational Diseases / prevention & control
  • Occupational Exposure / prevention & control*
  • Protective Devices
  • Respiratory Hypersensitivity / immunology
  • Respiratory Hypersensitivity / prevention & control
  • United States
  • Ventilation


  • Air Pollutants, Occupational
  • Allergens