Selective inhibition of CTL activation by a dipalmitoyl-phospholipid that prevents the recruitment of signaling molecules to lipid rafts

FASEB J. 2001 Jul;15(9):1601-3. doi: 10.1096/fj.00-0841fje.

Authors

D F Legler¹, M A Doucey, J C Cerottini, C Bron, I F Luescher

Affiliation

¹ Institute of Biochemistry and. Ludwig Institute for Cancer Research, Lausanne Branch, University of Lausanne, BIL Biomedical Research Center, CH-1066 Epalinges, Switzerland. daniel.legler@ib.unil.ch

PMID: 11427499
DOI: 10.1096/fj.00-0841fje

No abstract available

MeSH terms

Animals
Glycerophospholipids / pharmacology
Humans
Lymphocyte Activation / drug effects*
Membrane Microdomains / drug effects*
Membrane Microdomains / physiology
Mice
Phosphatidylethanolamines / pharmacology*
Signal Transduction
T-Lymphocytes, Cytotoxic / drug effects*
T-Lymphocytes, Cytotoxic / physiology
Tumor Cells, Cultured

Substances

1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine
Glycerophospholipids
Phosphatidylethanolamines
1,2-dipalmitoyl-3-phosphatidylethanolamine