The mouse SWISS-2D PAGE database: a tool for proteomics study of diabetes and obesity

Proteomics. 2001 Jan;1(1):136-63. doi: 10.1002/1615-9861(200101)1:1<136::AID-PROT136>3.0.CO;2-1.


A number of two-dimensional electrophoresis (2-DE) reference maps from mouse samples have been established and could be accessed through the internet. An up-to-date list can be found in WORLD-2D PAGE ( index.html), an index of 2-DE databases and services. None of them were established from mouse white and brown adipose tissues, pancreatic islets, liver nuclei and skeletal muscle. This publication describes the mouse SWISS-2D PAGE database. Proteins present in samples of mouse (C57BI/6J) liver, liver nuclei, muscle, white and brown adipose tissue and pancreatic islets are assembled and described in an accessible uniform format. SWISS-2D PAGE can be accessed through the World Wide Web (WWW) network on the ExPASy molecular biology server ( ch2d/).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Databases, Protein*
  • Diabetes Mellitus, Type 2 / genetics
  • Diabetes Mellitus, Type 2 / metabolism
  • Electrophoresis, Gel, Two-Dimensional
  • Mice
  • Mice, Inbred C57BL
  • Obesity / genetics
  • Obesity / metabolism
  • Peptide Mapping
  • Proteins / genetics
  • Proteins / isolation & purification
  • Proteome*
  • Tissue Distribution


  • Proteins
  • Proteome