Abstract
Four patients who had received silicone injections had the following complications: migration, hepatic disease manifested as granulomatous hepatitis (previously undescribed, to our knowledge), hypopigmentation, and death. Silicone should now be considered as a possible cause of hepatic granulomas in an appropriate host.
MeSH terms
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Adult
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Autopsy
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Female
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Granuloma / chemically induced
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Humans
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Injections / adverse effects
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Liver / drug effects
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Male
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Pigmentation Disorders / chemically induced
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Pulmonary Edema / chemically induced
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Pulmonary Edema / pathology
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Silicones / adverse effects*
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Simethicone / administration & dosage
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Simethicone / adverse effects*
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Simethicone / therapeutic use
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Skin / drug effects
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Surgery, Plastic