BRENDA: a resource for enzyme data and metabolic information

Trends Biochem Sci. 2002 Jan;27(1):54-6. doi: 10.1016/s0968-0004(01)02027-8.


BRENDA (BRaunschweig ENzyme DAtabase), founded in 1987 by Dietmar Schomburg, is a comprehensive protein function database, containing enzymatic and metabolic information extracted from the primary literature. Presently, the database holds data on more than 40 000 enzymes and 4460 different organisms, and includes information about enzyme-ligand relationships with numerous chemical compounds. The collection of molecular and biochemical information in BRENDA provides a fundamental resource for research in biotechnology, pharmacology, medicinal diagnostics, enzyme mechanics, and metabolism. BRENDA is accessible free of charge to the academic community at; commercial users need a license available from

Publication types

  • Review

MeSH terms

  • Animals
  • Databases, Factual*
  • Enzymes / chemistry*
  • Humans


  • Enzymes