Drug-induced extrapyramidal reactions

J Paediatr Child Health. 2002 Feb;38(1):95-7. doi: 10.1046/j.1440-1754.2002.00719.x.


A child with psychotic symptoms and attention-deficit hyperactivity disorder who developed extrapyramidal symptoms while on a combination of risperidone, methylphenidate, sertraline, tropisetron and ketorolac is described herein. The extrapyramidal symptoms resolved with the administration of benztropine, an anticholinergic drug. Successful treatment of his psychosis was achieved by decreasing the dose of risperidone, followed by slow upward titration.

Publication types

  • Case Reports

MeSH terms

  • Antipsychotic Agents / administration & dosage
  • Antipsychotic Agents / adverse effects*
  • Attention Deficit Disorder with Hyperactivity / complications
  • Attention Deficit Disorder with Hyperactivity / drug therapy*
  • Basal Ganglia Diseases / chemically induced*
  • Child
  • Drug Therapy, Combination
  • Humans
  • Male
  • New South Wales
  • Risperidone / administration & dosage
  • Risperidone / adverse effects*


  • Antipsychotic Agents
  • Risperidone