The TRP channels, a remarkably functional family

Cell. 2002 Mar 8;108(5):595-8. doi: 10.1016/s0092-8674(02)00670-0.


TRP cation channels display an extraordinary assortment of selectivities and activation mechanisms, some of which represent previously unrecognized modes for regulating ion channels. Moreover, the biological roles of TRP channels appear to be equally diverse and range from roles in pain perception to male aggression.

Publication types

  • Review

MeSH terms

  • Animals
  • Calcium Channels / classification
  • Calcium Channels / genetics
  • Calcium Channels / metabolism*
  • Humans
  • Models, Biological
  • Multigene Family
  • Protein Isoforms
  • Protein Structure, Secondary
  • Signal Transduction / physiology*
  • TRPC Cation Channels


  • Calcium Channels
  • Protein Isoforms
  • TRPC Cation Channels