Pheochromocytoma

Curr Treat Options Oncol. 2001 Aug;2(4):321-9. doi: 10.1007/s11864-001-0025-5.

Abstract

The only definitive therapy for patients with pheochromocytoma is surgical resection [1,2**]. Advances in preoperative medical management of hypertension/hypovolemia and improved intraoperative anesthetic care have reduced the operative mortality rate for pheochromocytoma to less than 5% in most series. In addition, accurate preoperative localization studies have eliminated the need for extensive exploratory laparotomy. Focused approach and laparoscopic resection have become the new "gold standard," with a reduced morbidity [4**]. Large or locally invasive pheochromocytomas may still require open resection.

Publication types

  • Review

MeSH terms

  • 3-Iodobenzylguanidine / therapeutic use
  • Adrenal Gland Neoplasms* / complications
  • Adrenal Gland Neoplasms* / diagnosis
  • Adrenal Gland Neoplasms* / metabolism
  • Adrenal Gland Neoplasms* / therapy
  • Adrenal Medulla / metabolism
  • Adrenalectomy / methods
  • Adrenergic alpha-Antagonists / therapeutic use
  • Antihypertensive Agents / therapeutic use
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Catecholamines / metabolism
  • Catecholamines / urine
  • Diagnostic Imaging
  • Humans
  • Hypertension / drug therapy
  • Hypertension / etiology
  • Laparoscopy
  • Metanephrine / urine
  • Neoplastic Syndromes, Hereditary
  • Palliative Care
  • Pheochromocytoma* / complications
  • Pheochromocytoma* / diagnosis
  • Pheochromocytoma* / metabolism
  • Pheochromocytoma* / therapy
  • Tachycardia / drug therapy
  • Tachycardia / etiology

Substances

  • Adrenergic alpha-Antagonists
  • Antihypertensive Agents
  • Catecholamines
  • 3-Iodobenzylguanidine
  • Metanephrine