Proximal aortic reoperations in patients with composite valve grafts

Ann Thorac Surg. 2002 Nov;74(5):S1777-80; discussion S1792-9. doi: 10.1016/s0003-4975(02)04152-8.

Abstract

Background: The purpose of this study was to examine our experience with proximal aortic reoperations in patients with composite valve grafts (CVGs) and assess postoperative survival and morbidity.

Methods: Since 1991, 33 patients with CVGs underwent reoperation for one or more of the following indications: aneurysms distal to the CVG (n = 20, 61%), false aneurysms (n = 13, 39%) and graft infection (n = 7, 21%). Operations included false aneurysm repair (n = 13, 39%), graft replacement of distal ascending aortic or transverse aortic arch aneurysm (n = 20, 61%) and aortic root re-replacement with a new CVG (n = 6, 18%) or homograft (n = 4, 12%).

Results: Operative mortality was 15% (n = 5), including 2 of the 7 patients who had infected CVGs (29%). All 4 patients who had infected CVGs replaced with aortic root homografts survived. Complications included vocal cord paralysis (n = 4, 12%), bleeding requiring reoperation (n = 3, 9%) and stroke (n = 2, 6%). Actuarial 3-year survival was 74.4% +/- 7.9%.

Conclusions: Reoperations in patients with CVGs remain challenging procedures with high associated morbidity and mortality, especially in the setting of graft infection. The results of homograft aortic root re-replacement for infected CVGs are encouraging.

MeSH terms

  • Adult
  • Aged
  • Aneurysm, False / mortality
  • Aneurysm, False / surgery*
  • Aortic Aneurysm, Thoracic / mortality
  • Aortic Aneurysm, Thoracic / surgery*
  • Blood Vessel Prosthesis Implantation*
  • Cause of Death
  • Female
  • Follow-Up Studies
  • Heart Valve Prosthesis Implantation*
  • Humans
  • Male
  • Marfan Syndrome / mortality
  • Marfan Syndrome / surgery
  • Middle Aged
  • Postoperative Complications / mortality
  • Postoperative Complications / surgery*
  • Prosthesis-Related Infections / mortality
  • Prosthesis-Related Infections / surgery*
  • Recurrence
  • Reoperation / mortality
  • Risk Factors
  • Transplantation, Homologous