Racial disparities in rectal cancer treatment: a population-based analysis

Arch Surg. 2004 Feb;139(2):151-5; discussion 156. doi: 10.1001/archsurg.139.2.151.

Abstract

Hypothesis: We hypothesized that there are significant racial disparities in delivery of care to rectal cancer patients. We examined differential surgical and radiation treatment for these patients and determined whether blacks were less likely than whites to undergo sphincter-sparing procedures, which are associated with a higher quality of life than sphincter-ablating procedures.

Design: Cross-sectional cohort study.

Patients and setting: The Surveillance Epidemiology and End Results database provided population-based data for rectal cancer patients who were diagnosed between 1988 and 1999, were older than 35 years, and had no prior colorectal or other pelvic cancer.

Main outcome measures: Using logistic regression, we compared receipt and type of surgical therapy and radiation therapy, controlling for age, sex, year, geography, stage, and anatomic location.

Results: Among 52 864 patients, 3851 were black and 44 010 were white. Blacks were younger than whites and had more advanced disease (P<.001). Among patients who underwent operation, rates of sphincter-ablating procedure were 37% for whites and 43% for blacks (adjusted odds ratio [AOR], 1.42; 95% confidence interval [CI], 1.23-1.65). Moreover, 53% of whites and 56% of blacks received no radiation therapy for stage II to III disease (AOR, 1.30; 95% CI, 1.15-1.47).

Conclusions: Blacks with rectal cancer were diagnosed at a younger age and more advanced disease stage than whites, implying a need for more aggressive screening. After adjusting for stage and other covariates, surgical and radiation treatment also differed along racial lines. Our data suggest that treatment disparities may contribute to differences in outcome among racial/ethnic groups with rectal cancer, and they highlight the need for improving access to state-of-the-art surgical care for minority patients with rectal cancer.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Black People / statistics & numerical data*
  • Black or African American
  • Cohort Studies
  • Colectomy / methods*
  • Colectomy / mortality
  • Confidence Intervals
  • Cross-Sectional Studies
  • Female
  • Health Care Surveys
  • Humans
  • Incidence
  • Logistic Models
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Odds Ratio
  • Postoperative Complications / epidemiology
  • Probability
  • Rectal Neoplasms / ethnology*
  • Rectal Neoplasms / mortality
  • Rectal Neoplasms / pathology
  • Rectal Neoplasms / surgery*
  • Risk Factors
  • SEER Program
  • Sex Factors
  • Socioeconomic Factors
  • Survival Analysis
  • United States
  • White People / statistics & numerical data*