Targeted radiotherapy of brain tumours

Br J Cancer. 2004 Apr 19;90(8):1469-73. doi: 10.1038/sj.bjc.6601771.


The utility of external beam radiotherapy for the treatment of malignant brain tumours is compromised by the need to avoid excessive radiation damage to normal CNS tissues. This review describes the current status of targeted radiotherapy, an alternative strategy for brain tumour treatment that offers the exciting prospect of increasing the specificity of tumour cell irradiation.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Antibodies, Monoclonal / therapeutic use
  • Astrocytoma / radiotherapy*
  • Brain Neoplasms / radiotherapy*
  • Clinical Trials as Topic
  • Glioblastoma / radiotherapy*
  • Humans
  • Radiation Injuries / prevention & control*
  • Radioimmunotherapy / methods


  • Antibodies, Monoclonal