Ocular photodynamic therapy in choroidal neovascularization complicating idiopathic central serous chorioretinopathy

Ophthalmic Surg Lasers Imaging. 2004 Mar-Apr;35(2):168-71.


Two consecutive patients with idiopathic central serous chorioretinopathy and decreased vision subsequent to subfoveal choroidal neovascular membranes were treated with photodynamic therapy applied using the protocol of the Treatment of Age-Related Macular Degeneration with Photodynamic Therapy Study Group. Main outcome measures included best-corrected visual acuity, biomicroscopic appearance, and leakage on fluorescein and indocyanine green angiography. Photodynamic therapy offered anatomical, angiographic, and functional improvement. After an initial complete response, the patients required re-treatment at 3 and 4 months, respectively. Cessation of leakage with improvement in visual acuity occurred, but subretinal fibrosis posed a possible limitation for full functional recovery. Although choroidal neovascular membranes complicating idiopathic central serous chorioretinopathy portend a poor visual prognosis, the overall response to photodynamic therapy was favorable.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Choroid Diseases / drug therapy*
  • Choroid Diseases / etiology
  • Choroidal Neovascularization / complications
  • Choroidal Neovascularization / drug therapy*
  • Coloring Agents
  • Female
  • Fluorescein Angiography
  • Humans
  • Indocyanine Green
  • Male
  • Middle Aged
  • Photochemotherapy*
  • Retinal Diseases / drug therapy*
  • Retinal Diseases / etiology
  • Visual Acuity


  • Coloring Agents
  • Indocyanine Green