Intraosseous meningioma: a rare cause of chronic optic neuropathy and exophthalmos

Klin Monbl Augenheilkd. 2004 May;221(5):414-7. doi: 10.1055/s-2004-812812.

Abstract

Background: The association of optic neuropathy, proptosis and chorioretinal folds is highly suggestive of an orbitopathy. Usual etiologies include an inflammatory orbitopathy, optic nerve sheath meningioma, sphenoid wing meningioma, exterioration of a sinus disorder, or an orbital tumor be it primary or secondary.

History and signs: A 40-year-old man treated for systemic hypertension complained of decreased vision and floaters in his right eye. Initial examination revealed decreased visual acuity to 20/50 of the right eye with a slight dyschromatopsia, but a lack of afferent pupillary defect and normal visual fields. Fundus examination showed the presence of a slightly swollen right optic disc and chorioretinal folds. A diagnosis of presumed anterior ischemic optic neuropathy was made. Symptoms persisted and, five months later, right proptosis was noted. Magnetic resonance imaging revealed a diffuse thickening of the parieto-temporal bone and the greater wing of the sphenoid bone on the right side. Radiological differential diagnosis included fibrous dysplasia and metastasis.

Therapy and outcome: Bone biopsy revealed a grade I intraosseous meningioma. Conservative management was chosen because the lesion was too extensive to be resected and radiotherapy is usually not efficient on grade I meningiomas.

Conclusions: Intraosseous meningiomas are benign tumors which are due to meningeal cells entrapment during vaginal delivery. It is a rare tumor of slow progression. Therapy usually consists of resection and cranioplasty and/or radiotherapy. In the present case, decompression of the optic canal remains feasible in case of further visual loss.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biopsy
  • Diagnosis, Differential
  • Exophthalmos / diagnosis
  • Exophthalmos / etiology*
  • Fluorescein Angiography
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Meningeal Neoplasms / complications*
  • Meningeal Neoplasms / diagnosis
  • Meningioma / complications*
  • Meningioma / diagnosis
  • Nerve Compression Syndromes / diagnosis
  • Nerve Compression Syndromes / etiology
  • Optic Nerve Diseases / diagnosis
  • Optic Nerve Diseases / etiology*
  • Parietal Bone* / pathology
  • Skull Neoplasms / complications*
  • Skull Neoplasms / diagnosis
  • Sphenoid Bone* / pathology
  • Temporal Bone* / pathology