Anticarcinogenic activity of Withania somnifera Dunal against Dalton's ascitic lymphoma

J Ethnopharmacol. 2004 Aug;93(2-3):359-61. doi: 10.1016/j.jep.2004.04.004.


The effect of ethanolic extract of the root of Withania somnifera Dunal (REWS) against Dalton's Ascitic Lymphoma has been evaluated in Swiss albino mice. A significant increase in the life span and a decrease in the cancer cell number and tumour weight were noted in the tumour-induced mice after treatment with REWS. The hematological parameters were also corrected by REWS in tumour-induced mice. These observations are suggestive of the protective effect of REWS in Dalton's Ascitic Lymphoma (DAL).

MeSH terms

  • Animals
  • Antineoplastic Agents, Phytogenic / administration & dosage
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Antineoplastic Agents, Phytogenic / therapeutic use
  • Ascites / drug therapy
  • Ascites / pathology
  • Lymphoma / drug therapy
  • Lymphoma / pathology
  • Mice
  • Neoplasm Transplantation
  • Neoplasms, Experimental / drug therapy
  • Neoplasms, Experimental / pathology
  • Peritoneal Cavity / cytology
  • Phytotherapy*
  • Plant Extracts / administration & dosage
  • Plant Extracts / pharmacology*
  • Plant Extracts / therapeutic use
  • Plant Roots
  • Withania*


  • Antineoplastic Agents, Phytogenic
  • Plant Extracts