Suppression of host defense in compatible plant-Pseudomonas syringae interactions

Curr Opin Plant Biol. 2005 Aug;8(4):361-8. doi: 10.1016/j.pbi.2005.05.005.


Despite impressive advances in the study of plant resistance to pathogens, little is known about the molecular basis of plant susceptibility to virulent pathogens. Recent progress in susceptible plant-Pseudomonas syringae interactions has provided a glimpse into the battles fought between plants and bacterial pathogens. A key step for pathogenesis appears to be the suppression of host defenses. Suppression of host defenses, including basal defense, gene-for-gene resistance and nonhost resistance, is a key step for pathogenesis. Defense suppression is mediated by bacterial effector proteins, which are secreted through the type III secretion system, and by coronatine, a bacterial toxin that structurally and functionally mimics methyl jasmonate, a plant defense signaling molecule.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Gene Expression Regulation, Plant
  • Immunity, Innate
  • Plant Diseases / microbiology*
  • Plants / genetics
  • Plants / immunology*
  • Pseudomonas syringae / pathogenicity
  • Pseudomonas syringae / physiology*
  • Signal Transduction
  • Virulence