Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Feb;114(2):260-3.
doi: 10.1289/ehp.8418.

Organic Diets Significantly Lower Children's Dietary Exposure to Organophosphorus Pesticides

Affiliations
Free PMC article

Organic Diets Significantly Lower Children's Dietary Exposure to Organophosphorus Pesticides

Chensheng Lu et al. Environ Health Perspect. .
Free PMC article

Abstract

We used a novel study design to measure dietary organophosphorus pesticide exposure in a group of 23 elementary school-age children through urinary biomonitoring. We substituted most of children's conventional diets with organic food items for 5 consecutive days and collected two spot daily urine samples, first-morning and before-bedtime voids, throughout the 15-day study period. We found that the median urinary concentrations of the specific metabolites for malathion and chlorpyrifos decreased to the nondetect levels immediately after the introduction of organic diets and remained nondetectable until the conventional diets were reintroduced. The median concentrations for other organophosphorus pesticide metabolites were also lower in the organic diet consumption days; however, the detection of those metabolites was not frequent enough to show any statistical significance. In conclusion, we were able to demonstrate that an organic diet provides a dramatic and immediate protective effect against exposures to organophosphorus pesticides that are commonly used in agricultural production. We also concluded that these children were most likely exposed to these organophosphorus pesticides exclusively through their diet. To our knowledge, this is the first study to employ a longitudinal design with a dietary intervention to assess children's exposure to pesticides. It provides new and persuasive evidence of the effectiveness of this intervention.

Figures

Figure 1
Figure 1
Box plots of DVWA of MDA concentrations in 23 children 3–11 years of age for 15 consecutive days in which conventional and organic diets were consumed. The top row of numbers on the x-axis represents numbers of children.
Figure 2
Figure 2
Box plots of DVWA of TCPY concentrations in 23 children 3–11 years of age for 15 consecutive days in which conventional and organic diets were consumed. The top row of numbers on the x-axis represents numbers of children.

Comment in

  • Organic diets and children's health.
    Avery A. Avery A. Environ Health Perspect. 2006 Apr;114(4):A210-A211; author reply A211. doi: 10.1289/ehp.114-a210b. Environ Health Perspect. 2006. PMID: 16581524 Free PMC article. No abstract available.
  • OP pesticides, organic diets, and children's health.
    Krieger RI, Keenan JJ, Li Y, Vega HM. Krieger RI, et al. Environ Health Perspect. 2006 Oct;114(10):A572; author reply A572-3. doi: 10.1289/ehp.114-a572a. Environ Health Perspect. 2006. PMID: 17035114 Free PMC article. No abstract available.

Similar articles

See all similar articles

Cited by 80 articles

See all "Cited by" articles

References

    1. Adgate JL, Clayton CA, Quackenboss JJ, Thomas KW, Whitmore RW, Pellizzari ED, et al. Measurement of multi-pollutant and multi-pathway exposures in a probability-based sample of children: practical strategies for effective field studies. J Expo Anal Environ Epidemiol. 2000;10:650–651. - PubMed
    1. Barr DB, Turner WE, DiPietro E, McClure PC, Baker SE, Barr JR, et al. Measurement of p-nitrophenol in the urine of residents whose homes were contaminated with methyl parathion. Environ Health Perspect. 2002;110:1085–1091. - PMC - PubMed
    1. Curl CL, Fenske RA, Elgethun K. Organophosphorus pesticide exposure of urban and suburban pre-school children with organic and conventional diets. Environ Health Perspect. 2003;111:377–382. - PMC - PubMed
    1. Fenske RA, Kedan G, Lu C, Fisker-Andersen JA, Curl CL. Assessment of organophosphorus pesticide exposures in the diets of preschool children in Washington State. J Expo Anal Environ Epidemiol. 2002;12:21–28. - PubMed
    1. Flower KB, Hoppin JA, Lynch CF, Blair A, Knott C, Shore DL, et al. Cancer risk and parental pesticide application in children of Agricultural Health Study participants. Environ Health Perspect. 2004;112:631–635. - PMC - PubMed

Publication types

Feedback