Caffeine as an ergogenic aid

Curr Sports Med Rep. 2006 Jun;5(4):215-9. doi: 10.1097/01.csmr.0000306510.57644.a7.


Caffeine is a naturally occurring substance that is widely consumed in a variety of forms. It produces multiple physiologic effects throughout the body. It is thought that this is mediated mainly through action at centrally located adenosine receptors. Caffeine has been studied for its potential use as an ergogenic aid. Several studies have demonstrated an improvement in exercise performance in submaximal endurance activities. Its potential ergogenic effect in acute, high-intensity exercise is less clear. Because of its potential use as an ergogenic aid, it use in sports is regulated by most sanctioning bodies.

Publication types

  • Review

MeSH terms

  • Caffeine / adverse effects
  • Caffeine / pharmacology*
  • Central Nervous System Stimulants / adverse effects
  • Central Nervous System Stimulants / pharmacology*
  • Humans
  • Physical Endurance / drug effects*
  • Receptors, Purinergic P1 / drug effects
  • Sports


  • Central Nervous System Stimulants
  • Receptors, Purinergic P1
  • Caffeine