A prolonged gestational intrahepatic cholestasis: a case report

Turk J Gastroenterol. 2006 Sep;17(3):206-8.


Gestational intrahepatic cholestasis, characterized by generalized pruritus and biochemical changes of cholestasis, usually occurs in the third trimester of pregnancy, persists until delivery and resolves spontaneously within the initial four weeks of the puerperium. The incidence is dependent on genetic basis, environmental factors and geographical location. We report the case of a patient with gestational intrahepatic cholestasis with an extraordinary clinical course that extended to the 82nd week postpartum.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cholagogues and Choleretics / therapeutic use
  • Cholestasis, Intrahepatic* / blood
  • Cholestasis, Intrahepatic* / drug therapy
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications* / blood
  • Pregnancy Complications* / drug therapy
  • Pregnancy Trimester, Third
  • Pruritus / etiology
  • Puerperal Disorders / blood
  • Puerperal Disorders / drug therapy
  • Ursodeoxycholic Acid / therapeutic use


  • Cholagogues and Choleretics
  • Ursodeoxycholic Acid