A possible link between prenatal exposure to famine and breast cancer: a preliminary study

Am J Hum Biol. 2006 Nov-Dec;18(6):853-6. doi: 10.1002/ajhb.20564.


In a study of 475 women born around the 1944-1945 Dutch famine, women exposed to prenatal famine more often reported a history of breast cancer than nonexposed women (hazard ratio, 2.6; 95% confidence interval, 0.9-7.7). They also had alterations in reproductive risk factors. Prenatal famine may increase breast cancer incidence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Birth Weight
  • Breast Neoplasms / epidemiology*
  • Breast Neoplasms / etiology
  • Cohort Studies
  • Female
  • Humans
  • Incidence
  • Maternal Nutritional Physiological Phenomena
  • Middle Aged
  • Netherlands / epidemiology
  • Pregnancy
  • Prenatal Exposure Delayed Effects*
  • Proportional Hazards Models
  • Starvation / physiopathology*
  • World War II