PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits

Nucleic Acids Res. 2007 Jan;35(Database issue):D51-4. doi: 10.1093/nar/gkl797. Epub 2006 Nov 11.

Abstract

Polymorphism in microRNA Target Site (PolymiRTS) database is a collection of naturally occurring DNA variations in putative microRNA target sites. PolymiRTSs may affect gene expression and cause variations in complex phenotypes. The database integrates sequence polymorphism, phenotype and expression microarray data, and characterizes PolymiRTSs as potential candidates responsible for the quantitative trait locus (QTL) effects. It is a resource for studying PolymiRTSs and their implications in phenotypic variations. PolymiRTS database can be accessed at http://compbio.utmem.edu/miRSNP/.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Databases, Nucleic Acid*
  • Gene Expression Profiling
  • Gene Expression Regulation
  • Humans
  • Internet
  • Mice
  • MicroRNAs / physiology*
  • Phenotype
  • Polymorphism, Single Nucleotide*
  • Quantitative Trait Loci
  • User-Computer Interface

Substances

  • MicroRNAs