Sudden change of a large congenital melanocytic nevus to neurocutaneous melanosis

J Craniofac Surg. 2006 Nov;17(6):1216-8. doi: 10.1097/01.scs.0000221514.34620.c0.

Abstract

Neurocutaneous melanosis (NCM) is a congenital phakomatosis in which large congenital melanocytic nevi are associated with a benign or malignant melanocytic tumor of the leptomeninges. Because the prognosis of patients with symptomatic NCM is poor, it is essential to monitor the large congenital melanocytic patient regularly for a neurological evaluation. However, it has not been reported how quickly the lesion could appear. We observed a case of NCM suddenly developing in a large congenital melanocytic nevi patient. With this case, the NCM had developed within six months and was aggravated during the subsequent six months.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Neoplasms / etiology*
  • Brain Neoplasms / surgery
  • Child
  • Fatal Outcome
  • Humans
  • Male
  • Melanoma / etiology*
  • Melanoma / surgery
  • Melanosis / etiology*
  • Neurocutaneous Syndromes / etiology*
  • Nevus, Pigmented / complications*
  • Skin Neoplasms / complications*