Autophagy in MHC class II presentation: sampling from within

Immunity. 2007 Jan;26(1):1-3. doi: 10.1016/j.immuni.2007.01.005.


MHC class II molecules usually present exogenous antigens, but peptidome analyses have also identified many antigens from cytosolic or nuclear sources. In this issue of Immunity, Schmid et al. show that MHC class II molecules can present these through autophagosomes.

Publication types

  • Comment
  • Review

MeSH terms

  • Animals
  • Antigen Presentation / immunology*
  • Autophagy / immunology*
  • Histocompatibility Antigens Class II / immunology*
  • Humans
  • Phagosomes / immunology


  • Histocompatibility Antigens Class II