Y-chromosome genetic structure in sub-Apennine populations of Central Italy by SNP and STR analysis

Int J Legal Med. 2007 May;121(3):234-7. doi: 10.1007/s00414-007-0153-y. Epub 2007 Feb 8.


To define the Y-chromosome genetic structure in Apennine populations, 17 Y-chromosome short tandem repeats (Y-STRs) and 37 Y-single nucleotide polymorphisms (Y-SNPs) were typed in 162 subjects living in the upland area of the Marches (Central Italy). A total number of 155 haplotypes (haplotype diversity was 0.9994) and 14 SNP haplogroups were observed. Testing high-resolution Y-chromosome data sets, e.g. using Yfiler and SNPs, increases the discriminatory capacity in individual identification for forensic purposes. It is also useful in autochthonous population and micro-population studies to highlight the most informative loci for evolutionary aims.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosomes, Human, Y*
  • DNA Fingerprinting
  • Genetics, Population*
  • Haplotypes
  • Humans
  • Italy
  • Male
  • Polymerase Chain Reaction
  • Polymorphism, Single Nucleotide*
  • Tandem Repeat Sequences*