A services oriented system for bioinformatics applications on the grid

Stud Health Technol Inform. 2007:126:174-83.


This paper describes the evolution of the main services of the ProGenGrid (Proteomics & Genomics Grid) system, a distributed and ubiquitous grid environment ("virtual laboratory"), based on Workflow and supporting the design, execution and monitoring of "in silico" experiments in bioinformatics.ProGenGrid is a Grid-based Problem Solving Environment that allows the composition of data sources and bioinformatics programs wrapped as Web Services (WS). The use of WS provides ease of use and fosters re-use. The resulting workflow of WS is then scheduled on the Grid, leveraging Grid-middleware services. In particular, ProGenGrid offers a modular bag of services and currently is focused on the biological simulation of two important bioinformatics problems: prediction of the secondary structure of proteins, and sequence alignment of proteins. Both services are based on an enhanced data access service.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Access to Information*
  • Computational Biology*
  • Internet
  • Italy
  • Medical Informatics*
  • Problem Solving
  • Proteomics