[Paraesthesia in the legs]

MMW Fortschr Med. 2007 Oct 18;149(42):49-52; quiz 53. doi: 10.1007/BF03365137.
[Article in German]


Paraesthesia in the legs can have numerous causes. In addition to the restless legs syndrome, other primary causes include venous insufficiency in the leg, propriospinal myoclonus, nocturnal leg cramps, peripheral polyneuropathy that affects mostly the legs or neuroleptic drug-induced akathisia. Through detailed questioning of the patient, restless legs syndrome can be specifically distinguished from the other named differential diagnoses.

Publication types

  • Comparative Study
  • English Abstract
  • Review

MeSH terms

  • Analgesics, Opioid / therapeutic use
  • Diagnosis, Differential
  • Dopamine Agents / therapeutic use
  • Humans
  • Levodopa / therapeutic use
  • Nocturnal Myoclonus Syndrome / diagnosis
  • Paresthesia* / diagnosis
  • Polyneuropathies / diagnosis
  • Psychomotor Agitation / diagnosis
  • Restless Legs Syndrome* / diagnosis
  • Restless Legs Syndrome* / drug therapy
  • Sleep-Wake Transition Disorders / diagnosis
  • Venous Insufficiency


  • Analgesics, Opioid
  • Dopamine Agents
  • Levodopa