Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. Sep-Oct 2007;20(5):314-21.
doi: 10.1111/j.1529-8019.2007.00145.x.

Interaction of Vitamins C and E as Better Cosmeceuticals

Affiliations
Review

Interaction of Vitamins C and E as Better Cosmeceuticals

Karen E Burke. Dermatol Ther. .

Abstract

Although many cosmeceutical formulations contain vitamin C and/or vitamin E, very few are actually effective in topical application. First because there is only a low concentration, second because the stability is compromised as soon as the product is opened and exposed to air and light, and third because the form of the molecule (an ester or a mixture of isomers) is not absorbed or metabolized effectively by the skin. However, when a stable formulation delivers a high concentration of the nonesterified, optimal isomer of the antioxidant, vitamins C and E do indeed inhibit the acute ultraviolet (UV) damage of erythema, sunburn, and tanning as well as chronic UV photoaging and skin cancer. Both are highly effective depigmenting agents. Topical vitamin C also increases collagen synthesis in both young and old fibroblasts. Because vitamin C regenerates oxidized vitamin E, the combination in a cosmeceutical formulation is synergistic - particularly in UV protection.

Similar articles

See all similar articles

Cited by 10 articles

See all "Cited by" articles

LinkOut - more resources

Feedback