Viral elements in autoimmunity of type I diabetes

Trends Endocrinol Metab. 1996 May-Jun;7(4):139-44. doi: 10.1016/1043-2760(96)00037-9.


The involvement of viruses in the etiology of insulin-dependent diabetes was hypothesized more than 15 years ago based on solid scientific evidence, however; the true existence and the real nature of this involvement still eludes our efforts. This may be due to the frequently long interval between viral exposure and diabetes onset that makes the direct cause-effect relationship difficult to prove.