Lyme disease: European perspective

Infect Dis Clin North Am. 2008 Jun;22(2):327-39, vii. doi: 10.1016/j.idc.2008.01.001.


The main clinical features of Lyme borreliosis seem to be the same in Europe and North America; however, the course of erythema migrans is distinct, with multiple erythema migrans and hematogeneous dissemination in early Lyme borreliosis less frequently observed in Europe. Moreover, the skin manifestations borrelial lymphocytoma and acrodermatitis chronica atrophicans are apparently European phenomena. Meningoradiculoneuritis in Lyme neuroborreliosis, with its severe radicular pain, is more prominent in Europe. Similar difficulties exist on both sides of the Atlantic with the serologic diagnosis of Lyme borreliosis.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Animals
  • Erythema Chronicum Migrans / diagnosis
  • Europe
  • History, 19th Century
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Lyme Disease* / diagnosis
  • Lyme Disease* / drug therapy
  • Lyme Disease* / history
  • Lyme Neuroborreliosis / diagnosis
  • Pseudolymphoma / microbiology