Inhibitors of sterol biosynthesis as Staphylococcus aureus antibiotics

Angew Chem Int Ed Engl. 2008;47(31):5700-2. doi: 10.1002/anie.200801801.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / metabolism
  • Farnesyl-Diphosphate Farnesyltransferase / metabolism
  • Staphylococcus aureus / metabolism*
  • Staphylococcus aureus / pathogenicity
  • Sterols / antagonists & inhibitors*
  • Sterols / biosynthesis
  • Virulence

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Sterols
  • CrtM protein, Staphylococcus aureus
  • Farnesyl-Diphosphate Farnesyltransferase