Cocoa butter lotion for prevention of striae gravidarum: a double-blind, randomised and placebo-controlled trial

BJOG. 2008 Aug;115(9):1138-42. doi: 10.1111/j.1471-0528.2008.01796.x.


Objective: To assess whether application of cocoa butter lotion reduces the development of striae gravidarum (SG).

Design: Multicentre, double-blind, randomised and placebo-controlled trial.

Setting: Beirut and Tripoli, Lebanon.

Population: Nulliparous women presenting for prenatal care.

Methods: Nulliparous women presenting in the first trimester were randomly assigned to receive a lotion containing cocoa butter or a placebo lotion. Women were instructed to apply the assigned lotion daily until delivery.

Main outcome measure: The development of striae over the abdomen, breasts and thighs postpartum.

Results: Of 210 women enrolled, 175 (83%) completed the study. Ninety-one women received the study lotion and 84 received the placebo. There was no difference in the development of SG (45.1% versus 48.8%; P = 0.730) or the severity of SG between cases and controls. The results did not change when presence of stretch marks at enrolment or compliance with the regimen were taken into account.

Conclusion: Topical application of a lotion containing cocoa butter does not appear to reduce the likelihood of developing striae gravidarum.

Trial registration: NCT00114660.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Topical
  • Adult
  • Dermatologic Agents / administration & dosage*
  • Dietary Fats / administration & dosage*
  • Double-Blind Method
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications / prevention & control*
  • Prenatal Care
  • Skin Diseases / prevention & control*


  • Dermatologic Agents
  • Dietary Fats
  • cocoa butter

Associated data