Chemotherapy in patients with penile carcinoma

Urol Int. 2009;82(1):1-7. doi: 10.1159/000176016. Epub 2009 Jan 20.


The prognosis of patients with advanced penile carcinoma is poor. There are only few studies, mostly with a low number of patients, which show a low response rate with severe toxicity. While adjuvant and palliative chemotherapy for penile cancer is universally characterized by low efficacy, neoadjuvant approaches for patients with fixed lymph node metastases have shown some response. Overall, recent experiences with new chemotherapeutic approaches (i.e. taxane-based combinations) have shown some encouraging results. Therefore, these combinations should be investigated in larger and multi-center studies.

Publication types

  • Review

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Chemotherapy, Adjuvant
  • Humans
  • Lymphatic Metastasis
  • Male
  • Neoadjuvant Therapy
  • Neoplasm Metastasis
  • Palliative Care
  • Penile Neoplasms / drug therapy*
  • Penile Neoplasms / mortality
  • Penile Neoplasms / pathology
  • Time Factors
  • Treatment Outcome