Levodopa delivery systems for the treatment of Parkinson's disease: an overview

Int J Pharm. 2009 Oct 1;380(1-2):1-15. doi: 10.1016/j.ijpharm.2009.07.026. Epub 2009 Aug 3.

Abstract

This review describes the different drug delivery systems containing levodopa that are used in the treatment of Parkinson's disease. Their composition, process of preparation, advantages, disadvantages and limitations are discussed as well as the major objective in the management of Parkinson's disease according to the pathology of the disease.

Publication types

  • Review

MeSH terms

  • Basal Ganglia / anatomy & histology
  • Basal Ganglia / metabolism
  • Basal Ganglia / pathology
  • Dopamine / metabolism
  • Dosage Forms
  • Drug Administration Routes
  • Drug Delivery Systems / methods*
  • Humans
  • Levodopa / administration & dosage*
  • Models, Neurological
  • Parkinson Disease / drug therapy*
  • Parkinson Disease / metabolism
  • Parkinson Disease / pathology

Substances

  • Dosage Forms
  • Levodopa
  • Dopamine