Esthetic outcome of surgical excision versus antibiotic therapy for nontuberculous mycobacterial cervicofacial lymphadenitis in children

Pediatr Infect Dis J. 2009 Nov;28(11):1028-30. doi: 10.1097/INF.0b013e3181aa6411.


One hundred children with microbiologically proven nontuberculous mycobacterial cervicofacial lymphadenitis were randomly assigned to excision of the involved lymph nodes, or antibiotic therapy consisting of clarithromycin and rifabutin. The esthetic outcome was rated using a revised and weighted Observer Scar Assessment Scale. The median weighted esthetic outcome in surgical patients was significantly better (30.6) than that for patients treated with antibiotics (42.2).

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / therapeutic use*
  • Child
  • Child, Preschool
  • Clarithromycin / therapeutic use
  • Female
  • Humans
  • Infant
  • Lymph Node Excision*
  • Lymphadenitis / drug therapy*
  • Lymphadenitis / surgery*
  • Male
  • Mycobacterium Infections / drug therapy*
  • Mycobacterium Infections / surgery*
  • Rifabutin / therapeutic use
  • Treatment Outcome


  • Anti-Bacterial Agents
  • Rifabutin
  • Clarithromycin