[Study of the relationship between the acupoints of Zhongzhu (TE 3), Yanglingquan (GB 34) and their corresponding cortical areas with the functional MRI]

Zhongguo Zhen Jiu. 2009 Jul;29(7):561-4.
[Article in Chinese]


Objective: Using the functional magnetic resonance imaging (fMRI) to observe the distributed characteristic of excited cerebral cortical areas that induced by acupuncture-stimulating the Zhongzhu (TE 3) of the meridian of Hand-Shaoyang and Yanglingquan (GB 34) of the meridian of Foot-Shaoyang, and investigate the central neural mechanism on the effect of meridians and acupoints.

Methods: Forty-two right handed healthy volunteers were randomly divided into Zhongzhu (TE 3) group and Yanglingquan (GB 34) group. The functional cortical changes during acupuncture-stimulating the Zhongzhu (TE 3) and Yanglingquan (GB 34) were successively scanned with fMRI, and the effected areas were determined through analysing the obtained data with SPM2 software.

Results: The main excited areas were bilateral frontal lobes, temporal lobes, cerebellum and occipital lobes successively in Zhongzhu (TE 3) group, and bilateral occipital lobes, cerebellum, frontal lobes and temporal lobes in Yanglingquan (GB 34) group in contrast.

Conclusion: Acupuncture-stimulating both Zhongzhu (TE 3) and Yanglingquan (GB 34) can excite bilateral acoustic, visual and somatomotor cortices, which might be the central neural basis for clinical treatment on related diseases.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acupuncture Points*
  • Adult
  • Cerebral Cortex / diagnostic imaging*
  • Cerebral Cortex / physiology*
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Meridians
  • Middle Aged
  • Radiography
  • Young Adult