Attitudes and behavior of peripheral arterial disease patients toward influencing their physician's prescription of cholesterol-lowering medication

Vasc Med. 2010 Apr;15(2):83-90. doi: 10.1177/1358863X09353653. Epub 2010 Jan 29.


Among 355 peripheral arterial disease (PAD) patients with low density lipoprotein cholesterol (LDL-C) levels > or = 70 mg/dl, we assessed knowledge regarding optimal LDL levels and the importance of LDL-C-lowering therapy. We also assessed PAD participants' behaviors and attitudes regarding their engagement with their physician in treatment decisions for LDL-C lowering. The average baseline LDL-C level of participants was 103.4 mg/dl +/- 30.7 mg/dl. Seventy-six percent of participants were taking at least one cholesterol-lowering medication. Sixty-six percent were unable to define their optimal LDL-C. Only 47% strongly agreed that their own actions and decisions could reduce their LDL-C. Just 29.8% were aware that patients who request specific medications from their physician were more likely to receive them, and 16% had asked their physician whether they should be taking more cholesterol-lowering medication. These findings suggest that further study is needed to identify effective interventions to educate PAD patients and their physicians about the importance of cholesterol-lowering therapy and to encourage PAD patients to participate with their physician in decisions regarding cholesterol-lowering treatment. Clinical Trial Registration - URL: Unique identifier: NCT00217919.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Aged, 80 and over
  • Ankle Brachial Index
  • Atherosclerosis / drug therapy
  • Atherosclerosis / metabolism
  • Atherosclerosis / psychology
  • Attitude to Health*
  • Cholesterol, LDL / blood*
  • Cholinergic Antagonists / therapeutic use*
  • Drug Prescriptions
  • Female
  • Health Behavior
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Male
  • Medication Adherence / psychology
  • Middle Aged
  • Patient Participation / psychology
  • Peripheral Arterial Disease / drug therapy*
  • Peripheral Arterial Disease / metabolism
  • Peripheral Arterial Disease / psychology*
  • Self Efficacy
  • Surveys and Questionnaires


  • Cholesterol, LDL
  • Cholinergic Antagonists

Associated data