Amyotrophic Lateral Sclerosis Overview

Excerpt

The purpose of this overview is to:

1. 1

   Describe the clinical characteristics of amyotrophic lateral sclerosis (ALS);

2. 2

   Review genetic causes of ALS;

3. 3

   Provide an evaluation strategy to identify the genetic cause of ALS in a proband (when possible);

4. 4

   Provide a high-level view of management of ALS;

5. 5

   Inform genetic counseling of family members of an individual with ALS.