Clinical chemistry and hematology values in a Caribbean population of African green monkeys

J Med Primatol. 2010 Dec;39(6):389-98. doi: 10.1111/j.1600-0684.2010.00422.x.


Background: Hematology and clinical chemistry (HCC) reference values are critical in veterinary practice and in vivo pre-clinical research, enabling detection of health abnormalities, response to therapeutic intervention or adverse toxicological effects, as well as monitoring of clinical management.

Methods: In this report, reference ranges for 46 HCC parameters were characterized in 331 wild-caught and colony-bred African green monkeys. Effects of sex, weight and duration of captivity were determined by one-way analysis of variance.

Results: Significant sex differences were observed for several HCC parameters. Significant differences were also observed for select HCC variables between newly caught animals and those held in captivity for 1-12 months or longer.

Conclusions: Comparison of this data with other non-human primate species and humans highlights similarities and disparities between species. Potential causes of interpopulation variability and relevance to the use of the African green monkey as a non-human primate model are discussed.

MeSH terms

  • Albumins / metabolism
  • Alkaline Phosphatase / blood
  • Animals
  • Aspartate Aminotransferases / blood
  • Bilirubin / blood
  • Blood Glucose
  • Body Weight
  • Caribbean Region
  • Chlorocebus aethiops / blood*
  • Chlorocebus aethiops / physiology*
  • Cholesterol / blood
  • Creatine Kinase / blood
  • Creatinine / blood
  • Female
  • Globulins / metabolism
  • Male
  • Minerals / blood
  • Sex Characteristics
  • Triglycerides / blood


  • Albumins
  • Blood Glucose
  • Globulins
  • Minerals
  • Triglycerides
  • Cholesterol
  • Creatinine
  • Aspartate Aminotransferases
  • Creatine Kinase
  • Alkaline Phosphatase
  • Bilirubin