Crizotinib--latest champion in the cancer wars?

N Engl J Med. 2010 Oct 28;363(18):1760-2. doi: 10.1056/NEJMe1010404.
No abstract available

Publication types

  • Editorial
  • Comment

MeSH terms

  • Anaplastic Lymphoma Kinase
  • Carcinoma, Non-Small-Cell Lung / drug therapy*
  • Carcinoma, Non-Small-Cell Lung / genetics
  • Cell Cycle Proteins / genetics*
  • Crizotinib
  • Drug Resistance, Neoplasm / genetics
  • Granuloma, Plasma Cell / drug therapy
  • Humans
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / genetics
  • Microtubule-Associated Proteins / genetics*
  • Mutation*
  • Protein-Tyrosine Kinases / antagonists & inhibitors*
  • Protein-Tyrosine Kinases / genetics
  • Pyrazoles / therapeutic use*
  • Pyridines / therapeutic use*
  • Receptor Protein-Tyrosine Kinases
  • Serine Endopeptidases / genetics*

Substances

  • Cell Cycle Proteins
  • Microtubule-Associated Proteins
  • Pyrazoles
  • Pyridines
  • Crizotinib
  • Anaplastic Lymphoma Kinase
  • Protein-Tyrosine Kinases
  • Receptor Protein-Tyrosine Kinases
  • EML4 protein, human
  • Serine Endopeptidases