Experimental and numerical study on the hemodynamics of stenosed carotid bifurcation

Australas Phys Eng Sci Med. 2010 Dec;33(4):319-28. doi: 10.1007/s13246-010-0050-4. Epub 2011 Jan 4.


Numerical simulation is performed to demonstrate that hemodynamic factors are significant determinants for the development of a vascular pathology. Experimental measurements by particle image velocimetry are carried out to validate the credibility of the computational approach. We present a study for determining complex flow structures using the case of an anatomically realistic carotid bifurcation model that is reconstructed from medical imaging. A transparent silicone replica of the artery is developed for in-vitro flow measurement. The dynamic behaviours of blood through the vascular structure based on the numerical and experimental approaches show good agreement.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Carotid Stenosis / pathology
  • Carotid Stenosis / physiopathology*
  • Computer Simulation
  • Hemorheology / physiology*
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Magnetic Resonance Angiography
  • Male
  • Models, Cardiovascular*
  • Phantoms, Imaging
  • Reproducibility of Results