Outcomes of immediate breast reconstruction in patients undergoing single-stage sentinel lymph node biopsy and mastectomy

Ann Plast Surg. 2011 May;66(5):564-7. doi: 10.1097/SAP.0b013e31820b406c.


The ability to more definitively plan breast reconstruction after obtaining final histologic analysis of the sentinel lymph node biopsy (SLNB) has led several groups to advocate a staged approach to SLNB and mastectomy. Certain disadvantages are inherent in that approach, including increased patient morbidity, financial expense, and inconvenience. A retrospective review was conducted 195 procedures in which mastectomy and SLNB were performed in a single stage with immediate breast reconstruction (IBR) over a 10-year period. Long-term outcomes were analyzed within the context of patient characteristics and SLNB results. Intraoperative SLNB analysis was found to be a reliable method for planning IBR, as there were no patients noted to have untoward sequelae as a result of a false-negative SLNB, and the probability of postmastectomy radiation therapy was predictable based on the intraoperative SLNB results. We advocate that SLNB be performed in a single stage with mastectomy and IBR.

Publication types

  • Evaluation Study

MeSH terms

  • Breast Neoplasms / mortality
  • Breast Neoplasms / pathology*
  • Breast Neoplasms / surgery*
  • Cohort Studies
  • Combined Modality Therapy
  • Disease-Free Survival
  • Female
  • Follow-Up Studies
  • Humans
  • Mammaplasty / adverse effects
  • Mammaplasty / methods*
  • Mastectomy / methods*
  • Mastectomy / mortality
  • Middle Aged
  • Neoplasm Invasiveness / pathology
  • Neoplasm Staging
  • Retrospective Studies
  • Risk Assessment
  • Sentinel Lymph Node Biopsy
  • Survival Rate
  • Time Factors
  • Treatment Outcome