Phenolics from Rhagadiolus stellatus (Asteraceae, Cichorieae)

Sci Pharm. 2011 Jan-Mar;79(1):175-9. doi: 10.3797/scipharm.1011-12. Epub 2011 Feb 7.


Rhagadiolus stellatus Gaertn., a Mediterranean member of the Cichorieae tribe of the Asteraceae family used as a food plant, was analyzed for its spectrum of phenolic compounds. Kaempferol 3-O-β-glucoside 1, kaempferol 3-O-β-rutinoside (nicotiflorin) 2, quercetin 3-O-β-glucoside 3, and luteolin 4 were isolated from the n-butanol layer of a methanolic extract of whole plants of Rh. stellatus of Spanish origin by repeated Sephadex LH-20 column chromatography. Structures were determined based on NMR and MS data as well as by comparison with literature data. Additionally, chlorogenic acid 5 and 3,5-dicaffeoylquinic acid 6 were detected by HPLC/DAD and HPLC/MS. Chemosystematic implications of the presented findings are discussed in comparison with other members of the Cichorieae tribe.

Keywords: Asteraceae; Chemosystematics; Cichorieae; Flavonoids; Rhagadiolus stellatus Gaertn..