Aggressive fibromatosis of the larynx: case report and brief review

J Int Med Res. 2011;39(2):682-9. doi: 10.1177/147323001103900239.

Abstract

Aggressive fibromatosis is a rare, benign, fibroblastic neoplasm, characterized by local invasion and a relatively high rate of recurrence. Here a case of laryngeal aggressive fibromatosis in a 47-year old man is reported. The patient presented with worsening dyspnoea and hoarseness and was hospitalized for treatment with partial laryngectomy. Final pathological evaluation of the tumour confirmed a diagnosis of aggressive fibromatosis. The patient has remained disease-free without further treatment for 5 years. This study demonstrated that aggressive fibromatosis may occur around the larynx and can be managed by partial laryngectomy alone. It is, therefore, important to include this rare disease entity in the routine differential diagnosis of laryngeal masses.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Fibromatosis, Aggressive / diagnostic imaging
  • Fibromatosis, Aggressive / pathology*
  • Fibromatosis, Aggressive / surgery
  • Humans
  • Immunohistochemistry
  • Laryngeal Neoplasms / diagnostic imaging
  • Laryngeal Neoplasms / pathology*
  • Laryngeal Neoplasms / surgery
  • Laryngoscopy
  • Larynx / diagnostic imaging
  • Larynx / pathology*
  • Larynx / surgery
  • Male
  • Middle Aged
  • Tomography, X-Ray Computed