Upper gastrointestinal bleeding in an end-stage renal disease patient treated with fluoxetine

Chia-Ta Chan; Sidney S Chang; Eng-Kung Yeh; Lih-Chih Jou

doi:10.1016/j.genhosppsych.2011.03.012

Upper gastrointestinal bleeding in an end-stage renal disease patient treated with fluoxetine

Gen Hosp Psychiatry. 2011 Sep-Oct;33(5):530.e1-3. doi: 10.1016/j.genhosppsych.2011.03.012. Epub 2011 May 20.

Authors

Chia-Ta Chan¹, Sidney S Chang, Eng-Kung Yeh, Lih-Chih Jou

Affiliation

¹ Department of Psychiatry, Shin Kong Wu Ho-Su Memorial Hospital, Taipei City 111, Taiwan (R.O.C.). paneth@mail2000.com.tw

PMID: 21749836
DOI: 10.1016/j.genhosppsych.2011.03.012

Abstract

The defective platelets of end-stage renal disease patients might be further incapacitated by the antiplatelet effect of selective serotonin reuptake inhibitor, and bleeding tendency in these patients could be aggravated. Here we demonstrate an end-stage renal disease patient who was admitted for duodenal ulcer bleeding during the treatment with fluoxetine, and the bleeding did not stop by various active treatments until the cessation of fluoxetine.

Publication types

Case Reports

MeSH terms

Aged
Bipolar Disorder / complications*
Bipolar Disorder / drug therapy*
Duodenal Ulcer*
Fluoxetine / adverse effects*
Fluoxetine / therapeutic use
Gastrointestinal Hemorrhage / chemically induced
Humans
Kidney Failure, Chronic / complications
Male
Peptic Ulcer Hemorrhage / chemically induced*
Peptic Ulcer Hemorrhage / therapy
Selective Serotonin Reuptake Inhibitors / adverse effects*
Selective Serotonin Reuptake Inhibitors / therapeutic use
Treatment Outcome

Substances

Serotonin Uptake Inhibitors
Fluoxetine