Malignant nature of cardiac liposarcoma revealed by fluorine-18 fluorodeoxyglucose positron emission tomographic imaging

Intern Med. 2012;51(11):1367-70. doi: 10.2169/internalmedicine.51.7242. Epub 2012 Jun 1.


Primary cardiac liposarcoma is very rare and usually asymptomatic. It is often diagnosed at an advanced or incurable stage without being presented in surgical operation. We report a man in his early sixties with primary cardiac liposarcoma originating from the ventricular septum. The malignant nature of the tumor was suspected by positron emission tomography using fluorine-18 fluorodeoxyglucose as the tracer. The final diagnosis was made histopathologically following surgery. Treatment with carbon ion radiotherapy was applied, but failed to induce tumor regression.

Publication types

  • Case Reports

MeSH terms

  • Fluorine Radioisotopes
  • Fluorodeoxyglucose F18
  • Heart Neoplasms / diagnosis
  • Heart Neoplasms / diagnostic imaging*
  • Heart Neoplasms / radiotherapy
  • Humans
  • Liposarcoma / diagnosis
  • Liposarcoma / diagnostic imaging*
  • Liposarcoma / radiotherapy
  • Male
  • Middle Aged
  • Positron-Emission Tomography
  • Radiopharmaceuticals
  • Treatment Failure


  • Fluorine Radioisotopes
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18